TAS4464 Size:10mg solid is a novel first in

is a novel first in class

WEHI-345 reduces mRNA levels of NF-kB targets such as TNF

TPR-MET cells by 44

BI-2536 treatment ranging from 10 nM to 100 nM leads to the blocking of the recruitment of γ-tubulin and phosphorylation of Apc6 at mitotic centrosomes

TAS4464 Size:10mg solid is a novel first inTAS4464 is a potent and highly selective NEDD8 activating enzyme (NAE) inhibitor with IC50 of 0. 955 nM. TAS4464 exhibits superior antitumor activity with prolonged target inhibition. Product information CAS Number: 1848959 10 3 Molecular Weight: 506. 51 Formula: C21H23FN6O6S Synonym: TAS 4464 TAS 4464 Chemical Name: 7H Pyrrolo[2,3 d]pyrimidin 4 amine, 7 [5 [(aminosulfonyl)amino] 5 deoxy beta D ribofuranosyl] 5 [2 (2 ethoxy 6 fluorophenyl)ethynyl]