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GSK2656157 - CAS# 1337532-29-2 Size:Solid 10 mg PRI-724 is phosphorylated-C-82 and is

GSK2656157 - CAS# 1337532-29-2 Size:Solid 10 mg PRI-724 is phosphorylated-C-82 and is

Name: GSK2656157 - CAS# 1337532-29-2 Size:Solid 10 mg PRI-724 is phosphorylated-C-82 and is
Brand: schmucketriebe.at
SKU: 6713777898
Price: 85.00 USD
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SKU: 6713777898

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GSK2656157 - CAS# 1337532-29-2 Size:Solid 10 mg PRI-724 is phosphorylated-C-82 and isGSK2656157 is an ATP competitive inhibitor of PERK enzyme activity with an IC50 of 0. 9 nM. It is highly selective for PERK with IC50 values >100 nM against a panel of 300 kinases. GSK2656157 inhibits PERK activity in cells with an IC50 in the range of 10 30 nM as shown by inhibition of stress induced PERK autophosphorylation, eIF2 substrate phosphorylation, together with corresponding decreases in ATF4 and CHOP proteins in multiple cell lines. Oral

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Description

PRI-724 is phosphorylated-C-82 and is rapidly hydrolyzed to its active form C-82 in vivo

Formula: C35H45N7O8S

VU-0458298-2

Amlexanox increases phosphorylation of TBK1 on Ser172 in 3T3-L1 adipocytes

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