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Odanacatib - CAS# 603139-19-1 Catalog No.:M6428-C 1431280-51-1

Odanacatib - CAS# 603139-19-1 Catalog No.:M6428-C 1431280-51-1

Name: Odanacatib - CAS# 603139-19-1 Catalog No.:M6428-C 1431280-51-1
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Odanacatib - CAS# 603139-19-1 Catalog No.:M6428-C 1431280-51-1Odanacatib, also known as MK 0822, CAS No. 603139 19 1, is an inhibitor of cathepsin K with potential anti osteoporotic activity. Odanacatib selectively binds to and inhibits the activity of cathepsin K, which may result in a reduction in bone resorption, improvement of bone mineral density, and a reversal in osteoporotic changes. Cathepsin K, a tissue specific cysteine protease that catalyzes degradation of bone matrix proteins such as collagen I II,

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Description

1431280-51-1

Formula: C18H11BrN2O2

reduces sickling and prolongs RBC half-life in a murine model of sickle cell disease

and then the animals are tail vein injected with IGF to stimulate Akt phosphorylation

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