Lasmiditan Catalog No.:M10338-10 3)4)35-26(38)11-9-7-5-6-8-10-12-27(39)40/h13-16
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Lasmiditan Catalog No.:M10338-10 3)4)35-26(38)11-9-7-5-6-8-10-12-27(39)40/h13-16Lasmiditan, also known as COL 144 and LY573144, is a novel, centrally acting, highly selective 5 HT(1F) receptor agonist (K1=2. 21 M) without vasoconstrictor activity that seemed effective when given as an intravenous infusion in a proof of concept migraine study. Lasmiditan showed efficacy in its primary endpoint, with a 2 hour placebo subtracted headache response of 28. 8%, though with frequent reports of dizziness, paresthesias, and vertigo.
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