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Regorafenib Hydrochloride - CAS# 835621-07-3 Catalog No.:M10444-10 6-tert-butyl-3a-carboxyhexahydro-alpha5a

Regorafenib Hydrochloride - CAS# 835621-07-3 Catalog No.:M10444-10 6-tert-butyl-3a-carboxyhexahydro-alpha5a

Name: Regorafenib Hydrochloride - CAS# 835621-07-3 Catalog No.:M10444-10 6-tert-butyl-3a-carboxyhexahydro-alpha5a
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Regorafenib Hydrochloride - CAS# 835621-07-3 Catalog No.:M10444-10 6-tert-butyl-3a-carboxyhexahydro-alpha5aRegorafenib (Stivarga, BAY 73 4506) Hydrochloride is a multi target inhibitor for VEGFR1, Murine VEGFR2 3, PDGFR, Kit (c Kit), RET (c RET) and Raf 1 with IC50 of 13 nM, 4. 2 nM 46 nM, 22 nM, 7 nM, 1. 5 nM and 2. 5 nM, respectively. Product information CAS Number: 835621 07 3 Molecular Weight: 519. 28 Formula: C21H16Cl2F4N4O3 Synonym: BAY73 4506 hydrochloride Chemical Name: 4 [4 ({[4 chloro 3 (trifluoromethyl)phenyl]carbamoyl}amino) 3 fluorophenoxy] N

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Description

6-tert-butyl-3a-carboxyhexahydro-alpha5a

and GlyH-101"

1314890-29-3

ARRY-520 had low nanomolar antiproliferative activity in tumor cell lines and specifically inhibits KSP (kinesin-5 or Eg5)

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