AZD2858 46040 4-dihydroxy-6-methyl-5-{[(1S

4-dihydroxy-6-methyl-5-{[(1S

and 100 mg/kg) elicits a dose-dependent decrease in serum human GH levels

Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting religation of DNA breaks

Smiles: CC1=C(CC(O)=O)C2=CC=CN=C2N1CC1=CC=C(C=C1C(F)(F)F)S(C)(=O)=O

AZD2858 46040 4-dihydroxy-6-methyl-5-{[(1SAZD2858 is a potent and GSK 3 inhibitor with an IC50 of 68 nM. AZD 2858 inhibits tau phosphorylation at the S396 site, and it activates Wnt signaling pathway. AZD2858 has a substantial impact on fracture healing. The fractures healed with a bony callus without an obvious endochondral component, suggesting that AZD2858 drives mesenchymal cells into the osteoblastic pathway. Product information CAS Number: 486424 20 8 Molecular Weight: 453. 52 Formula: