PF 4800567 erase Inhibitor II reduced splenomegaly

reduced splenomegaly

4-dioxobutan-2-yl)-3-((S)-2-(3-(tert-butyl)ureido)-3

Smiles: CC1SC(=CC=1[C@@H]1NCCC2=CC=C(Cl)C=C21)C(=O)C1=CN=CN=C1N[C@@H]1C[C@H](COS(N)(=O)=O)[C@@H](O)C1

PubMed PMID: 24758416

PF 4800567 erase Inhibitor II reduced splenomegalyPF 4800567 is a novel and potent inhibitor of casein kinase 1 epsilon (IC50=32 nM) with greater than 20 fold selectivity over casein kinase 1 delta(IC50=711 nM). Product information CAS Number: 1188296 52 7 Molecular Weight: 359. 81 Formula: C17H18ClN5O2 Chemical Name: 3 [(3 chlorophenoxy)methyl] 1 (oxan 4 yl)pyrazolo[3,4 d]pyrimidin 4 amine Smiles: NC1=NC=NC2=C1C(COC1C=C(Cl)C=CC=1)=NN2C1CCOCC1 InChiKey: AUMDBEHGJRZSOO UHFFFAOYSA N InChi: InChI=1S