NMS-1286937 Catalog No.:M9125-2 Selective TGF-β1/ALK inhibitor improves neuronal
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NMS-1286937 Catalog No.:M9125-2 Selective TGF-β1/ALK inhibitor improves neuronalOnvansertib, also know as NMS P937, PCM 075 and NMS1286937, is a n orally bioavailable, small molecule Polo like kinase 1 (PLK1) inhibitor with potential antineoplastic activity. Polo like kinase 1 inhibitor NMS 1286937 selectively inhibits PLK1, inducing selective G2 M cell cycle arrest followed by apoptosis in a variety of tumor cells while causing reversible cell cycle arrest at the G1 and G2 stages without apoptosis in normal cells. PLK1
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