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Vinflunine tartrate Size:Solid 10 mg CAS Number: 1197300-24-5

SKU: 95834621591

4.4
SEK119.00 SEK154.00

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Vinflunine tartrate Size:Solid 10 mg CAS Number: 1197300-24-5Vinflunine is a bi fluorinated derivative of the semi synthetic vinca alkaloid vinorelbine with antitubulin, antineoplastic, and antiangiogenic activities. Vinflunine inhibits tubulin assembly without any stablization of assembled microtubules at concentrations comparable to those of other vinca alkaloids such as vincristine, vinblastine and vinorelbine; this effect on microtubule dynamics results in cell cycle arrest in mitosis and apoptosis.

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Description

CAS Number: 1197300-24-5

At higher concentrations it is also an efficient inhibitor of serine/threonine protein kinases (IC50 of 10 to 30 nmol/L)

57Dihydroxyflavone

1056901-62-2

Vinflunine tartrate Size:Solid 10 mg CAS Number: 1197300-24-5Vinflunine is a bi fluorinated derivative of the semi synthetic vinca alkaloid vinorelbine with antitubulin, antineoplastic, and antiangiogenic activities. Vinflunine inhibits tubulin assembly without any stablization of assembled microtubules at concentrations comparable to those of other vinca alkaloids such as vincristine, vinblastine and vinorelbine; this effect on microtubule dynamics results in cell cycle arrest in mitosis and apoptosis.

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