OCLN Polyclonal Antibody, 100ul High Speed Micro-Centrifuges MIM: 151410)

MIM: 151410)

The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia

The encoded protein acts as an effector of signaling pathways that regulate apoptosis and tumor cell growth

The encoded protein promotes intracellular localization of the mTOR complex

OCLN Polyclonal Antibody, 100ul High Speed Micro-Centrifuges MIM: 151410)This gene encodes an integral membrane protein that is required for cytokine induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band like calcification with simplified gyration and polymicrogyria (BLC PMG), an autosomal recessive neurologic disorder that is also known as pseudo TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene