AZ1 Polyclonal Antibody, 100ul Reservoirs Mutations in this gene can

Mutations in this gene can result in B cell deficiency and agammaglobulinemia

all encoding the same protein

This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins

SOX proteins have been implicated in cell fate decisions in a diverse range of developmental processes

AZ1 Polyclonal Antibody, 100ul Reservoirs Mutations in this gene canThe protein encoded by OAZ1 belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto regulatory circuit. OAZ1