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Consequently, VRK2 expression emerges as a dual-function biomarker: its targeted inhibition shows therapeutic efficacy in VRK2-high malignancies, while its deficiency serves as a predictive indicator for metabolic-targeted interventions

The DOX/LAAM GSH-CQDs accumulated in the tumor within 30 min and lasted for 24 h, and the fluorescence intensities in the DOX/LAAM GSH-CQDs were two to three times higher than those found for free DOX in the tumors (Supplementary Fig

Certain ingredients may interfere with copper peptide effectiveness , reducing their benefits

Moreover, H 2 O 2 -triggered lesions on the leaves of cat2 can be reverted by blocking SA synthesis through the isochorismate pathway or by treating leaves with myo -inositol, but in neither case does the suppression of cell death correlate with less oxidized tissue glutathione status (Chaouch and Noctor, 2010