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young shoots), standardized to 85% silicon dioxide, pyridoxal-5'-phosphate (vitamin B6), chromium picolinate, L-methylfolate calcium (folic acid), methylcobalamin (vitamin B12)

Once the tumour became arrested in the palbociclib-treated group, mice were further randomized to receive either RSL3 (50 mg kg 1 , two times per week for 2 weeks) or the vehicle, resulting in four experimental groups: vehicle, RSL3, palbociclib and palbociclib + RSL3