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Caroline Apovian, then at Boston University School of Medicine, noted in a 2015 review of anti-obesity pharmacotherapy that "clinicians must monitor nutritional intake when combining agents that independently reduce appetite, particularly when one agent carries seizure liability" [8]

[PUBMED Abstract] Ciccarese G, Dalmasso B, Bruno W, et al.: Clinical, pathological and dermoscopic phenotype of MITF p.E318K carrier cutaneous melanoma patients